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Proteomics approaches are essential to study diseases at a protein level in both clinical and basic research. They help in understanding underlying disease mechanisms and identifying specific molecular signatures.


Founded in 2006, PPN is part of SFR Necker and the network of proteomic platforms of University of Paris. The PPN is labeled IBiSA, a consortium composed of the CEA, CNRS, CPU, INCa, INRAE, Inria, Inserm and the MESR, whose objective is to promote the implementation of new technologies by supporting selected platforms.


PPN’s mission is to enable academic teams to succeed in their proteomics projects. The platform is open to research institutes, clinical departments and the private sector – in France and abroad.


The instrument park of the PPN has been renewed in 2021 and now includes a timsTOF Pro mass spectrometer which can be coupled to EvosepOne or nanoElute LC systems, dedicated to high throughput analysis and quantification of proteins. The platform also has a Biolayer interferometry instrument.


In 2023, Necker Proteomics has introduced a new technology dedicated to plasma biomarker research: Proteograph from Seer. The Proteograph Assay is based on the formation of a protein corona on functionalized nanoparticles, which dramatically increases the number of plasma proteins quantified by mass spectrometry (from 800 to over 4000) (Learn more at


PPN is the only laboratory in France offering this new technology, and has attained the label of a "reference laboratory" for Seer in Europe.

The dynamic interaction between the Precision Medicine Proteomics Lab and the Necker Proteomic Platform offers state of the art technology and expertise to help understanding disease (PTMs, differential and interaction proteomics) and to search for diagnostic/prognostic biomarkers in body fluids by MS (high-throughput LC-MSMS, EVs analysis).


The PPN platform has adopted a quality management approach in order to optimize its organization, guarantee the traceability of all information concerning projects and provide its collaborators with the most reliable results.

Since February 2023 PPN is certified according to the requirements of the quality management standards ISO 9001:2016 and NF X50-900:2016. The certification covers all of PPN's areas of activity : « Services and research & development activities in clinical and translational proteomics » (ISO and NFX LRQA Certificates).



Plateforme Protéomique PPN Necker

Faculté de Médecine Université de Paris Cité

156-160 rue de Vaugirard

75015 Paris


Tél : 01 40 61 54 67


PPN Necker is at 1st flour of the Faculty building


Ciara G_edited.jpg
Chiara Guerrera, PhD
Alain Charbit, PhD

Scientific referent​

Cerina Chhuon

IE-Université de Paris Cité

Joanna Lipecka
Vincent Jung
Ines Metatla
Kevin Roger
Sara Ceccacci


Timms TOF-2.jpg

TimsTOF Pro MS (Bruker)


coupled to EVOSEPOne 



Expertises and services :

  • Advice to researchers and design of strategy adapted to their project

  • Identification of proteins for simple or complex samples

  • Identification and quantification of proteins (Labelfree SILAC, ITRAQ,)

  • Quantification of proteins (MRM and PRM)

  • Proteomic analysis of body fluids and extracellular vesicles (urine, BAL, sweat, plasma, amniotic fluid, CSF)

  • Statistical and bioinformatic analysis(Mascot, MaxQuant, Perseus software)

  • Biological analysis using protein network graph (Ingenuity software, AmiGO)


Applications :


  • Identification of new protein-protein, RNA-protein, DNA-protein interactions

  • Identification and quantification of PTMs (acetylation, glycosylation, phosphorylation)

  • Study of the differential proteome in the disease vs control

  • Multiple dosage of known proteins

  • Discovery and validation of biomarkers

  • Quality controls of recombinant proteins




80 publications in total, of which 45 publications since 2018 (average IF 2022: 9.74). For the full list of  publications click here.


*** publication en 1er ou dernier auteur par les ingénieurs de la plateforme


  1. The pentose phosphate pathway constitutes a major metabolic hub in pathogenic Francisella. Rytter H, Jamet A, Ziveri J, Ramond E, Coureuil M, Lagouge-Roussey P, Euphrasie D, Tros F, Goudin N, Chhuon C, Nemazanyy I, de Moraes FE, Labate C, Guerrera IC, Charbit A. PLoS Pathog. 2021 Aug 2;17(8):e1009326.

  2. RESVEGA, a Nutraceutical Omega-3/Resveratrol Supplementation, Reduces Angiogenesis in a Preclinical Mouse Model of Choroidal Neovascularization. Courtaut F, Aires V, Acar N, Bretillon L, Guerrera IC, Chhuon C, Pais de Barros JP, Olmiere C, Delmas D. Int J Mol Sci. 2021 Oct 13;22(20):11023.

  3. STING protects breast cancer cells from intrinsic and genotoxic-induced DNA instability via a non-canonical, cell-autonomous pathway. Cheradame L, Guerrera IC, Gaston J, Schmitt A, Jung V, Goudin N, Pouillard M, Radosevic-Robin N, Modesti M, Judde JG, Cairo S, Goffin V. Oncogene. 2021 Oct 8.

  4. Polo-like kinase 1 (Plk1) regulates DNA replication origin firing and interacts with Rif1 in Xenopus. Ciardo D, Haccard O, Narassimprakash H, Cornu D, Guerrera IC, Goldar A, Marheineke K. Nucleic Acids Res. 2021 Sep 27;49(17):9851-9869.

  5. Synaptic disruption and CREB-regulated transcription are restored by K+ channel blockers in ALS. Catanese A, Rajkumar S, Sommer D, Freisem D, Wirth A, Aly A, Massa-López D, OlivieriA, Torelli F, Ioannidis V, Lipecka J, Guerrera IC, Zytnicki D, Ludolph A, Kabashi E, Mulaw MA, Roselli F, Böckers TM. EMBO Mol Med. 2021 Jul 7;13(7):e13131.

  6. Identification and Relative Quantification of hFSH Glycoforms in Women's Sera via MS-PRM-Based Approach. Melchiorre C, Chhuon C, Jung V, Lipecka J, Di Rella F, Conforti A, Amoresano A, Carpentieri A, Guerrera IC. Pharmaceutics. 2021 May 27;13(6):798.

  7. Glucose treatment of human pancreatic β-cells enhances translation of mRNAs involved in energetics and insulin secretion. Zakaria A, Berthault C, Cosson B, Jung V, Guerrera IC, Rachdi L, Scharfmann R. J Biol Chem. 2021 Jul;297(1):100839.

  8. Integrative Cell Type-Specific Multi-Omics Approaches Reveal Impaired Programs of Glial Cell Differentiation in Mouse Culture Models of DM1. González-Barriga A, Lallemant L, Dincã DM, Braz SO, Polvèche H, Magneron P, Pionneau C, Huguet-Lachon A, Claude JB, Chhuon C, Guerrera IC, Bourgeois CF, Auboeuf D, Gourdon G, Gomes-Pereira M. Front Cell Neurosci. 2021 May 5;15:662035.

  9. Role of VAMP7-dependent secretion of reticulon 3 in neurite growth. Wojnacki J, Nola S, Bun P, Cholley B, Filippini F, Pressé MT, Lipecka J, Lam SM, N'guyen J, Simon A, Ouslimani A, Shui G, Fader CM, Colombo MI, Guerrera IC, Galli T. Cell Rep. 2021 Apr 13;35(2):109006.

  10. Sickle Cell Trait Modulates the Proteome and Phosphoproteome of Plasmodium falciparum-Infected Erythrocytes.Chauvet M, Chhuon C, Lipecka J, Dechavanne S, Dechavanne C, Lohezic M, Ortalli M, Pineau D, Ribeil JA, Manceau S, Le Van Kim C, Luty AJF, Migot-Nabias F, Azouzi S, Guerrera IC, Merckx A. Front Cell Infect Microbiol. 2021 Mar 24;11:637604.

  11. The equilibrative nucleoside transporter 1 (ENT1) is critical for nucleotide homeostasis and optimal erythropoiesis. Mikdar M, Gonzalez-Menendez P, Cai X, Zhang Y, Serra M, Dembélé AK, Boschat AC, Sanquer S, Chhuon C, Guerrera IC, Sitbon M, Hermine O, Colin Y, Le Van Kim C, Kinet S, Narla M, Xia Y, Peyrard T, Taylor N, Azouzi S. Blood. 2021 Mar 10:blood.2020007281. doi: 10.1182/blood.2020007281. Epub ahead of print. PMID: 33690842.

  12. Disruption of pathways regulated by Integrator complex in Galloway-Mowat syndrome due to WDR73 mutations. Tilley FC, Arrondel C, Chhuon C, Boisson M, Cagnard N, Parisot M, Menara G, Lefort N, Guerrera IC, Bole-Feysot C, Benmerah A, Antignac C, Mollet G. Sci Rep. 2021 Mar 8;11(1):5388. doi: 10.1038/s41598-021-84472-7. PMID: 33686175; PMCID: PMC7940485.

  13. Role of VAMP7-Dependent Secretion of Reticulon 3 in Neurite Growth. Wojnacki J, Nola S, Bun P, Cholley B, Filippini F, Pressé MT, Lipecka J, Man Lam S, N'guyen J, Simon A, Ouslimani A, Shui G, Fader CM, Colombo MI, Guerrera IC, Galli T. Cell Rep. 2020 Dec 22;33(12):108536. doi: 10.1016/j.celrep.2020.108536. PMID: 33357422.

  14. GFOGER Peptide Modifies the Protein Content of Extracellular Vesicles and Inhibits Vascular Calcification. Mansour A, Darwiche W, Yaker L, Da Nascimento S, Gomila C, Rossi C, Jung V, Sonnet P, Kamel S, Guerrera IC, Boullier A, Ausseil JFront Cell Dev Biol. 2020 Nov 30;8:589761. doi: 10.3389/fcell.2020.589761. PMID: 33330469; PMCID: PMC7734313.

  15. Dataset of a comparative proteomics experiment in a methylmalonyl-CoA mutase knockout HEK 293 cell model. Costanzo M, Caterino M, Cevenini A, Jung V, Chhuon C, Lipecka J, Fedele R, Guerrera IC, Ruoppolo M. Data Brief. 2020 Oct 22;33:106453. doi: 10.1016/j.dib.2020.106453. PMID: 33195772; PMCID: PMC7644733.

  16. Urinary Exosomes of Patients with Cystic Fibrosis Unravel CFTR-Related Renal Disease. Gauthier S, Pranke I, Jung V, Martignetti L, Stoven V, Nguyen-Khoa T, Semeraro M, Hinzpeter A, Edelman A, Guerrera IC, Sermet-Gaudelus I. Int J Mol Sci. 2020 Sep 10;21(18):6625. doi: 10.3390/ijms21186625. PMID: 32927759; PMCID: PMC7554933.

  17. *** A sensitive S-Trap-based approach to the analysis of T cell lipid raft proteome. Chhuon C, Zhang SY, Jung V, Lewandowski D, Lipecka J, Pawlak A, Sahali D, Ollero M, Guerrera IC. J Lipid Res. 2020 Nov;61(11):1512-1523. doi: 10.1194/jlr.D120000672. Epub 2020 Aug 7. PMID: 32769147; PMCID: PMC7604723.

  18. Proteomics Reveals that Methylmalonyl-CoA Mutase Modulates Cell Architecture and Increases Susceptibility to Stress. Costanzo M, Caterino M, Cevenini A, Jung V, Chhuon C, Lipecka J, Fedele R, Guerrera IC, Ruoppolo M. Int J Mol Sci. 2020 Jul 15;21(14):4998. doi: 10.3390/ijms21144998. PMID: 32679819; PMCID: PMC7403994.

  19. Critical Role of a Sheath Phosphorylation Site On the Assembly and Function of an Atypical Type VI Secretion System. Ziveri J, Chhuon C, Jamet A, Rytter H, Prigent G, Tros F, Barel M, Coureuil M, Lays C, Henry T, Keep NH, Guerrera IC, Charbit A. Mol Cell Proteomics. 2019 Dec;18(12):2418-2432. doi: 10.1074/mcp.RA119.001532. Epub 2019 Oct 2. PMID: 31578219; PMCID: PMC6885697.

  20. STK38 kinase acts as XPO1 gatekeeper regulating the nuclear export of autophagy proteins and other cargoes.  Martin AP, Jacquemyn M, Lipecka J, Chhuon C, Aushev VN, Meunier B, Singh MK, Carpi N, Piel M, Codogno P, Hergovich A, Parrini MC, Zalcman G, Guerrera IC, Daelemans D, Camonis JH. EMBO Rep. 2019 Nov 5;20(11):e48150. doi: 10.15252/embr.201948150.

  21. Defects in t6A tRNA modification due to GON7 and YRDC mutations lead to Galloway-Mowat syndrome.  Arrondel, Missoury, Snoek, Patat, Menara, Collinet, Liger, Durand, Gribouval, Boyer, Buscara, Martin, Machuca, Nevo, Lescop, Braun, Boschat, Sanquer, Guerrera IC, Revy, Parisot, Masson, BODDAERT, Charbit, Decramer, Novo, Macher, Ranchin, Bacchetta, Laurent, Collardeau-Frachon, Albertien van Eerde, Hildebrandt, Magen, Antignac, van Tilbeurgh, and Mollet.  Nat Commun. 2019 Sep 3;10(1):3967. doi: 10.1038/s41467-019-11951-x

  22. Intracellular offsprings released from SFB filaments are flagellated. Nkamba I, Mulet C, Dubey GP, Gorgette O, Couesnon A, Salles A, Moya-Nilges M, Jung V, Gaboriau-Routhiau V, Guerrera IC, Shima T, Umesaki Y, Nigro G, Krijnse-Locker J, Berard M, Cerf-Bensussan1 N, Sansonetti PJ, Schnupf P., Nat Microbiol. 2020 Jan;5(1):34-39. doi: 10.1038/s41564-019-0608-1.

  23. CMIP is a negative regulator of T cell signaling. Oniszczuk J, Sendeyo K, Chhuon C, Savas B, Cogné E, Vachin P, Henique C, Guerrera IC, Astarita G, Frontera V, Pawlak A, Audard V, Sahali D, Ollero M. Cell Mol Immunol. 2019 Aug 8. doi: 10.1038/s41423-019-0266-5. PubMed PMID: 31395948.

  24. Essential role of GEXP15, a specific Protein Phosphatase type 1 partner, in Plasmodium berghei in asexual erythrocytic proliferation and transmission. Hollin T, De Witte C, Fréville A, Guerrera IC, Chhuon C, Saliou JM, Herbert F, Pierrot C, Khalife J. PLoS Pathogens 2019 Jul 26;15(7):e1007973. doi:10.1371/journal.ppat.1007973. PMID: 31348803

  25. Plasmodium pseudo-Tyrosine Kinase-like binds PP1 and SERA5 and is exported to host erythrocytes Gnangnon B, Fréville A, Cailliau K, Leroy C, De Witte C, Tulasne D, Martoriarti A, Jung V, Guerrera IC, Marion S, Khalife J, Pierrot C. Sci Rep. 2019 May 31;9(1):8120. doi: 10.1038/s41598-019-44542-3. PubMed PMID: 31148576;

  26. Human IFT52 mutations uncover a novel role for the protein in microtubule dynamics and centrosome cohesion. Dupont MA, Humbert C, Huber C, Siour Q, Guerrera IC, Jung V, Christensen A, Pouliet A, Garfa-Traore M, Nitschké P, Injeyan M, Millar K, Chitayat D, Shannon P, Girisha KM, Shukla A, Mechler C, Lorentzen E, Benmerah A, Cormier-Daire V, Jeanpierre C, Saunier S, Delous M. Hum Mol Genet. 2019. pii: ddz091. doi: 10.1093/hmg/ddz091.

  27. Interaction between galectin-3 and cystinosin uncovers a pathogenic role of inflammation in kidney involvement of cystinosis. Lobry T, Miller R, Nevo N, Rocca CJ, Zhang J, Catz SD, Moore F, Thomas L, Pouly D, Bailleux A, Guerrera IC, Gubler MC, Cheung WW, Mak RH, Montier T, Antignac C, Cherqui S. Kidney Int. 2019 Mar 6. pii: S0085-2538(19)30172-3. doi: 10.1016/j.kint.2019.01.029.

  28. Chronic Staphylococcus aureus lung infection correlates with proteogenomic and metabolic adaptations leading to an increased intracellular persistence. Tan X, Coureuil M, Ramond E, Euphrasie D, Dupuis M, Tros F, Meyer J, Nemazanyy I, Chhuon C, Guerrera IC, Ferroni A, Sermet-Gaudelus I, Nassif X, Charbit A, Jamet A. Clin Infect Dis. 2019 Feb 7. doi: 10.1093/cid/ciz106.

  29. LC-MS/MS-based quantification of efflux transporter proteins at the BBB. Gomez-Zepeda D, Taghi M, Smirnova M, Sergent P, Liu WQ, Chhuon C, Vidal M, Picard M, Thioulouse E, Broutin I, Guerrera IC, Scherrmann JM, Parmentier Y, Decleves X, Menet MC. J Pharm Biomed Anal. 2019 Feb 5;164:496-508. doi: 10.1016/j.jpba.2018.11.013. Epub 2018 Nov 8.

  30. ***High N-glycan multiplicity is critical for neuronal adhesion and sensitizes the developing cerebellum to N-glycosylation defect. Medina-Cano D, Ucuncu E, Nguyen LS, Nicouleau M, Lipecka J, Bizot JC, Thiel C, Foulquier F, Lefort N, Faivre-Sarrailh C, Colleaux L, Guerrera IC, Cantagrel V. Elife. 2018 Oct 12;7. pii: e38309. doi: 10.7554/eLife.38309.

  31. ***Comparative proteomics of respiratory exosomes in cystic fibrosis, primary ciliary dyskinesia and asthma. Rollet-Cohen V, Bourderioux M, Lipecka J, Chhuon C, Jung V, Mesbahi M, Nguyen-Khoa T, Guérin-Pfyffer S, Schmitt A, Edelman A, Sermet-Gaudelus I, Guerrera IC. J Proteomics. 2018 Aug 15;185:1-7. doi: 10.1016/j.jprot.2018.07.001. Epub 2018 Jul 3.PMID: 30032860

  32. M’baya-Moutoulaa, E, Louveta, L, Moliniéb R, Guerrera IC, Cerutti C, Fourdinier O, Nourrye V, Gutierrez L, Morlière P, Mesnard F, Ziad A.M., Metzinger-le Meutha V. , and Metzinger L (2018). A multi-omics analysis of the regulatory changes induced by miR-223 in a monocyte/macrophage cell line. Biochim Biophys Acta Mol Basis Dis. 2018 Aug;1864(8):2664-2678. doi: 10.1016/j.bbadis.2018.05.010.

  33. ***Rollet-Cohen, V., Bourderioux, M., Lipecka, J; Chhuon, C., Mesbahi M, Nguyen-Khoa, T; Guérin-Pfyffer, S.; Schmitt, A; Edelman, A; Sermet-Gaudelus, I, Guerrera, IC. (2018) Comparative proteomics of respiratory exosomes in Cystic Fibrosis, Primary Ciliary Dyskinesia and Asthma. J Proteomics. 2018 Aug 15;185:1-7. doi: 10.1016/j.jprot.2018.07.001

  34. Braun, D. A., Rao, J., Mollet, G., Schapiro, D., Daugeron, M.-C., Tan, W., Gribouval, O., Boyer, O., Revy, P., Jobst-Schwan, T., Schmidt, J. M., Lawson, J. A., Schanze, D., Ashraf, S., Ullmann, J. F. P., Hoogstraten, C. A., Boddaert, N., Collinet, B., Martin, G., Liger, D., Lovric, S., Furlano, M., Guerrera, I. C., Sanchez-Ferras, O., Hu, J. F., Boschat, A.-C., Sanquer, S., Menten, B., Vergult, S., De Rocker, N., Airik, M., Hermle, T., Shril, S., Widmeier, E., Gee, H. Y., Choi, W.-I., Sadowski, C. E., Pabst, W. L., Warejko, J. K., Daga, A., Basta, T., Matejas, V., Scharmann, K., Kienast, S. D., Behnam, B., Beeson, B., Begtrup, A., Bruce, M., Ch’ng, G.-S., Lin, S.-P., Chang, J.-H., Chen, C.-H., Cho, M. T., Gaffney, P. M., Gipson, P. E., Hsu, C.-H., Kari, J. A., Ke, Y.-Y., Kiraly-Borri, C., Lai, W.-M., Lemyre, E., Littlejohn, R. O., Masri, A., Moghtaderi, M., Nakamura, K., Ozaltin, F., Praet, M., Prasad, C., Prytula, A., Roeder, E. R., Rump, P., Schnur, R. E., Shiihara, T., Sinha, M. D., Soliman, N. A., Soulami, K., Sweetser, D. A., Tsai, W.-H., Tsai, J.-D., Topaloglu, R., Vester, U., Viskochil, D. H., Vatanavicharn, N., Waxler, J. L., Wierenga, K. J., Wolf, M. T. F., Wong, S.-N., Leidel, S. A., Truglio, G., Dedon, P. C., Poduri, A., Mane, S., Lifton, R. P., Bouchard, M., Kannu, P., Chitayat, D., Magen, D., Callewaert, B., van Tilbeurgh, H., Zenker, M., Antignac, C., and Hildebrandt, F. (2017) Mutations in KEOPS-complex genes cause nephrotic syndrome with primary microcephaly. Nat. Genet. 49, 1529–1538

  35. Duriez, M., Mandouri, Y., Lekbaby, B., Wang, H., Schnuriger, A., Redelsperger, F., Guerrera, C. I., Lefevre, M., Fauveau, V., Ahodantin, J., Quetier, I., Chhuon, C., Gourari, S., Boissonnas, A., Gill, U., Kennedy, P., Debzi, N., Sitterlin, D., Maini, M. K., Kremsdorf, D., and Soussan, P. (2017) Alternative splicing of hepatitis B virus: A novel virus/host interaction altering liver immunity. J. Hepatol. 67, 687–699

  36. Gomez-Zepeda, D., Chaves, C., Taghi, M., Sergent, P., Liu, W.-Q., Chhuon, C., Vidal, M., Picard, M., Thioulouse, E., Broutin, I., Guerrera, I.C., Scherrmann, J.-M., Parmentier, Y., Decleves, X., and Menet, M.-C. (2017) Targeted unlabeled multiple reaction monitoring analysis of cell markers for the study of sample heterogeneity in isolated rat brain cortical microvessels. J. Neurochem. 142, 597–609

  37. Sicot, G., Servais, L., Dinca, D. M., Leroy, A., Prigogine, C., Medja, F., Braz, S. O., Huguet-Lachon, A., Chhuon, C., Nicole, A., Gueriba, N., Oliveira, R., Dan, B., Furling, D., Swanson, M. S., Guerrera, I. C., Cheron, G., Gourdon, G., and Gomes-Pereira, M. (2017) Downregulation of the Glial GLT1 Glutamate Transporter and Purkinje Cell Dysfunction in a Mouse Model of Myotonic Dystrophy. Cell Rep 19, 2718–2729

  38. ***Nevo, N., Thomas, L., Chhuon, C., Andrzejewska, Z., Lipecka, J., Guillonneau, F., Bailleux, A., Edelman, A., Antignac, C., and Guerrera, I. C. (2017) Impact of Cystinosin Glycosylation on Protein Stability by Differential Dynamic Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC). Mol. Cell Proteomics 16, 457–468

  39. Ziveri, J., Tros, F., Guerrera, I. C., Chhuon, C., Audry, M., Dupuis, M., Barel, M., Korniotis, S., Fillatreau, S., Gales, L., Cahoreau, E., and Charbit, A. (2017) The metabolic enzyme fructose-1,6-bisphosphate aldolase acts as a transcriptional regulator in pathogenic Francisella. Nat Commun 8, 85

  40. Meijer, B. M., Jang, S. M., Guerrera, I. C., Chhuon, C., Lipecka, J., Reisacher, C., Baleux, F., Sansonetti, P. J., Muchardt, C., and Arbibe, L. (2017) Threonine eliminylation by bacterial phosphothreonine lyases rapidly causes cross-linking of mitogen-activated protein kinase (MAPK) in live cells. J. Biol. Chem. 292, 7784–7794

  41. ***Chhuon, C., Pranke, I., Borot, F., Tondelier, D., Lipecka, J., Fritsch, J., Chanson, M., Edelman, A., Ollero, M., and Guerrera, I. C. (2016) Dataset of differential lipid raft and global proteomes of SILAC-labeled cystic fibrosis cells upon TNF -α stimulation. Data Brief 9, 51–56

  42. ***Chhuon, C., Pranke, I., Borot, F., Tondelier, D., Lipecka, J., Fritsch, J., Chanson, M., Edelman, A., Ollero, M., and Guerrera, I. C. (2016) Changes in lipid raft proteome upon TNF-α stimulation of cystic fibrosis cells. J Proteomics 145, 246–253

  43. ***Lipecka, J., Chhuon, C., Bourderioux, M., Bessard, M.-A., van Endert, P., Edelman, A., and Guerrera, I. C. (2016) Sensitivity of mass spectrometry analysis depends on the shape of the filtration unit used for filter aided sample preparation (FASP). Proteomics 16, 1852–1857

  44. ***Andrzejewska, Z., Nevo, N., Thomas, L., Chhuon, C., Bailleux, A., Chauvet, V., Courtoy, P. J., Chol, M., Guerrera, I. C., and Antignac, C. (2015) Cystinosin is a Component of the Vacuolar H+-ATPase-Ragulator-Rag Complex Controlling Mammalian Target of Rapamycin Complex 1 Signaling. J. Am. Soc. Nephrol.,

  45. Aoufouchi, S., De Smet, A., Delbos, F., Gelot, C., Guerrera, I. C., Weill, J.-C., and Reynaud, C.-A. (2015) 129-Derived Mouse Strains Express an Unstable but Catalytically Active DNA Polymerase Iota Variant. Mol. Cell. Biol. 35, 3059–3070

  46. Ramond, E., Gesbert, G., Guerrera, I. C., Chhuon, C., Dupuis, M., Rigard, M., Henry, T., Barel, M., and Charbit, A. (2015) Importance of host cell arginine uptake in Francisella phagosomal escape and ribosomal protein amounts. Mol. Cell Proteomics 14, 870–881

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