The Necker Federative Research Structure (SFR Necker), supported by four founding institutions : AP-HP, CNRS, Inserm, and Université Paris Cité ; aims to develop
and optimize technological core facilities and to foster scientific collaboration
and coordination on the Necker campus.

The SFR Necker brings together two research institutes : the Imagine Institute
of Genetic Diseases and the Necker Institute for Sick Children (INEM), as well as one research unit : the Integrated Biology of Red Blood Cells and Erythropoiesis (BIGR) ;
and nine hospital departments.

The Imagine Institute hosts 24 research teams, primarily focused on the study of rare constitutional diseases. INEM includes 20 teams investigating the cellular and molecular mechanisms of disease at the crossroads of immunity, metabolism, infection, regeneration, and gene regulation. The BIGR unit, comprising four research teams, completes this ecosystem with a focus on innovative research into red blood cell disorders and erythropoiesis.

All these teams conduct cutting-edge research in close synergy with the clinical activities of the Necker site. Their goal is to improve our understanding of the physiopathology of chronic human diseases, enhance diagnostic and therapeutic strategies, and develop innovative treatments.

The SFR Necker plays a central role by pooling financial and human resources to serve the entire scientific community of the campus, fostering a high-level, collaborative research environment aligned with both basic and clinical research objectives.
 

The platforms

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The platforms include Proteomics, Cell Imaging, Cytometry, Biological Resource Center, Bioinformatics, Viral Vectors for Gene Transfer (VVTG), Genomics, Genome Editing, Histology, Metabolic Analysis, Neuro Behavior, Iconography, Image Analysis Center and LEAT.

 

Through their service, collaboration, and research and development activities, Necker's platforms offer cutting-edge technology and expertise to help understand the disease and develop clinical diagnostic / prognostic tests. Each platform has a scientific referent and a manager. Steering committees or user committees are set up by the platforms according to their needs.

 

Eighty eight employees currently work for the various SFR Necker platforms.

 

These platforms play a crucial role by pooling the financial and human resources made available to scientists to enable them to remain competitive and achieve their research objectives.

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Organisation chart can be found here